USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: GSTM2_HUMAN USC-OGP 2-DE database:  GSTM2_HUMAN GSTM2_HUMAN General information about the entry View entry in simple text format Entry name GSTM2_HUMAN Primary accession number P28161 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Glutathione S-transferase Mu 2; EC=2.5.1.18; AltName: Full=GST class-mu 2; AltName: Full=GSTM2-2;. Gene name Name=GSTM2 Synonyms=GST4 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_6-11 {PLATELET 6-11} Homo sapiens (Human)   map experimental info   PLATELET_6-11 MAP LOCATIONS: SPOT OGP-1019: pI=5.93; Mw=24956 Cross-references UniProtKB/Swiss-Prot P28161; GSTM2_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name GSTM2_HUMAN Primary accession number P28161 Secondary accession number(s) B4DRY4 E9PEM9 Q2M318 Q5TZY5 Q8WWE1 Sequence was last modified on  January 23, 2007 (version 2) Annotations were last modified on  March 15, 2017 (version 176) Name and origin of the protein Description RecName: Full=Glutathione S-transferase Mu 2; EC=2.5.1.18; AltName: Full=GST class-mu 2; AltName: Full=GSTM2-2; Gene name Name=GSTM2 Synonyms=GST4 Encoded on Name=GSTM2; Synonyms=GST4 Keywords 3D-structure; Alternative splicing; Complete proteome; Cytoplasm; Direct protein sequencing; Phosphoprotein; Polymorphism; Reference proteome; Transferase. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL M63509; AAA60963.1; -; mRNA EMBL AK299482; BAG61446.1; -; mRNA EMBL BT019947; AAV38750.1; -; mRNA EMBL AC000031; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL AC000032; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL BC105038; AAI05039.1; -; mRNA EMBL BC105066; AAI05067.1; -; mRNA CCDS CCDS44192.1; -. [P28161-2]; . CCDS CCDS808.1; -. [P28161-1]; . PIR A39375; A39375; . RefSeq NP_000839.1; NM_000848.3. [P28161-1]; . RefSeq NP_001135840.1; NM_001142368.1. [P28161-2]; . UniGene Hs.279837; -; . PDB 1HNA; X-ray; 1.85 A; A=2-218 PDB 1HNB; X-ray; 3.50 A; A/B=2-218 PDB 1HNC; X-ray; 3.00 A; A/B/C/D=2-218 PDB 1XW5; X-ray; 1.80 A; A/B=2-218 PDB 1YKC; X-ray; 2.10 A; A/B=2-218 PDB 2AB6; X-ray; 2.50 A; A/B/C/D=2-218 PDB 2C4J; X-ray; 1.35 A; A/B/C/D=2-218 PDB 2GTU; X-ray; 2.55 A; A/B=2-218 PDB 3GTU; X-ray; 2.80 A; A/C=2-218 PDB 3GUR; X-ray; 2.50 A; A/B/C/D=2-218 PDBsum 1HNA; -; . PDBsum 1HNB; -; . PDBsum 1HNC; -; . PDBsum 1XW5; -; . PDBsum 1YKC; -; . PDBsum 2AB6; -; . PDBsum 2C4J; -; . PDBsum 2GTU; -; . PDBsum 3GTU; -; . PDBsum 3GUR; -; . ProteinModelPortal P28161; -; . SMR P28161; -; . BioGrid 109201; 6; . IntAct P28161; 2; . STRING 9606.ENSP00000241337; -; . BindingDB P28161; -; . ChEMBL CHEMBL4589; -; . DrugBank DB00143; Glutathione; . DrugBank DB03310; Oxidized Glutathione Disulfide; . DrugBank DB04701; S-METHYL-GLUTATHIONE; . SwissLipids SLP:000001614; -; . iPTMnet P28161; -; . PhosphoSitePlus P28161; -; . BioMuta GSTM2; -; . DMDM 232204; -; . OGP P28161; -; . REPRODUCTION-2DPAGE P28161; -; . EPD P28161; -; . MaxQB P28161; -; . PaxDb P28161; -; . PeptideAtlas P28161; -; . PRIDE P28161; -; . DNASU 2946; -; . Ensembl ENST00000241337; ENSP00000241337; ENSG00000213366. [P28161-1]; . Ensembl ENST00000442650; ENSP00000416883; ENSG00000213366. [P28161-2]; . Ensembl ENST00000460717; ENSP00000435910; ENSG00000213366. [P28161-2]; . GeneID 2946; -; . KEGG hsa:2946; -; . UCSC uc001dyj.4; human. [P28161-1]; . CTD 2946; -; . DisGeNET 2946; -; . GeneCards GSTM2; -; . HGNC HGNC:4634; GSTM2; . HPA CAB040547; -; . HPA HPA055972; -; . HPA HPA055973; -; . MIM 138380; gene; . neXtProt NX_P28161; -; . OpenTargets ENSG00000213366; -; . PharmGKB PA29023; -; . eggNOG ENOG410IN5J; Eukaryota; . eggNOG ENOG4110YU0; LUCA; . GeneTree ENSGT00550000074559; -; . HOGENOM HOG000115735; -; . HOVERGEN HBG106842; -; . InParanoid P28161; -; . KO K00799; -; . OMA RITESWA; -; . PhylomeDB P28161; -; . TreeFam TF353040; -; . BRENDA 2.5.1.18; 2681; . Reactome R-HSA-156590; Glutathione conjugation; . SABIO-RK P28161; -; . ChiTaRS GSTM2; human; . EvolutionaryTrace P28161; -; . GeneWiki GSTM2; -; . GenomeRNAi 2946; -; . PRO PR:P28161; -; . Proteomes UP000005640; Chromosome 1; . Bgee ENSG00000213366; -; . CleanEx HS_GSTM2; -; . ExpressionAtlas P28161; baseline and differential; . Genevisible P28161; HS; . GO GO:0005737; C:cytoplasm; IDA:BHF-UCL; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0016529; C:sarcoplasmic reticulum; IDA:BHF-UCL; . GO GO:0019899; F:enzyme binding; IPI:BHF-UCL; . GO GO:0043295; F:glutathione binding; IDA:BHF-UCL; . GO GO:0004602; F:glutathione peroxidase activity; IDA:BHF-UCL; . GO GO:0004364; F:glutathione transferase activity; IDA:UniProtKB; . GO GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL; . GO GO:0005102; F:receptor binding; IPI:BHF-UCL; . GO GO:0070458; P:cellular detoxification of nitrogen compound; IDA:BHF-UCL; . GO GO:0071313; P:cellular response to caffeine; IDA:BHF-UCL; . GO GO:1901687; P:glutathione derivative biosynthetic process; TAS:Reactome; . GO GO:0006749; P:glutathione metabolic process; IDA:UniProtKB; . GO GO:0043651; P:linoleic acid metabolic process; IDA:BHF-UCL; . GO GO:0060315; P:negative regulation of ryanodine-sensitive calcium-release channel activity; IDA:BHF-UCL; . GO GO:0018916; P:nitrobenzene metabolic process; IDA:BHF-UCL; . GO GO:0060316; P:positive regulation of ryanodine-sensitive calcium-release channel activity; IDA:BHF-UCL; . GO GO:0010881; P:regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; IC:BHF-UCL; . GO GO:0010880; P:regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; IDA:BHF-UCL; . GO GO:0014809; P:regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion; IC:BHF-UCL; . GO GO:0055119; P:relaxation of cardiac muscle; TAS:BHF-UCL; . GO GO:0042178; P:xenobiotic catabolic process; IDA:UniProtKB; . Gene3D 1.20.1050.10; -; 1; . Gene3D 3.40.30.10; -; 1; . InterPro IPR010987; Glutathione-S-Trfase_C-like; . InterPro IPR004045; Glutathione_S-Trfase_N; . InterPro IPR004046; GST_C; . InterPro IPR003081; GST_mu; . InterPro IPR012336; Thioredoxin-like_fold; . Pfam PF00043; GST_C; 1; . Pfam PF02798; GST_N; 1; . PRINTS PR01267; GSTRNSFRASEM; . SUPFAM SSF47616; SSF47616; 1; . SUPFAM SSF52833; SSF52833; 1; . PROSITE PS50405; GST_CTER; 1; . PROSITE PS50404; GST_NTER; 1; .

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